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| Caption | (A) Left: Sarcoma from the hind left limb of an 89-week-old male Wif1tm1Dmth/Wif1tm1Dmth mouse, arising adjacent to periosteum, and infiltrating skeletal muscle. The adjacent cortical bone (black arrow) and skeletal muscle fiber surrounded by sarcoma cells (red arrow) are indicated. Right: Osteosarcoma from the lumbar spine of a 56-week-old female homozygous mutant mouse, showing a malignant osteoid (yellow arrow). Scale bars: 100 um. (B) Radiation-induced osteosarcoma model schematic. (C) Typical imaging appearance of osteosarcomas. Top: 18F-PET scan demonstrating intense avidity of osteoblastic tumors from the same mouse. Bottom: Histology of mouse radiation-induced osteosarcoma. Original magnification, x20. | ||||
| Copyright | This image is from Kansara M, J Clin Invest 2009 Apr;119(4):837-51 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:149607 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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