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Phenotype Image Detail
Image
Caption Histological analysis of kidneys revealing nephrocalcinosis in Cldn10tm1.1Dmu/Cldn10tm1.1Dmu Tg(Cdh16-cre)91Igr/0 kidneys (A, B, and D) compared with kidneys from control mice (C and E). Von Kossa (A-C) and alizarin red S (D and E) staining show a characteristic calcification pattern in both stripes of the outer medulla in mutant kidney sections. (Scale bars: 1 mm in A-C; 0.4 mm in D and E).
Copyright This image is from Breiderhoff T, Proc Natl Acad Sci U S A 2012 Aug 28;109(35):14241-6. Copyright 2012 National Academy of Sciences, U.S.A. J:188580
Associated
Alleles
Symbol Name
Cldn10tm1.1Dmu claudin 10; targeted mutation 1.1, Dominik Muller
Tg(Cdh16-cre)91Igr transgene insertion 91, Peter Igarashi
Associated
Genotypes
Allelic Composition Genetic Background
Cldn10tm1.1Dmu/Cldn10tm1.1Dmu
Tg(Cdh16-cre)91Igr/0
involves: C57BL/6 * ICR * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory