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Phenotype Image Detail
Image
Caption The bones of Sosttm1(KOMP)Vlcg/Sosttm1(KOMP)Vlcg (SostKO) and Rr20tm1.1Vlcg/Rr20tm1.1Vlcg (ECR5KO) mice had higher bone mineral density (BMD) than wild-type (WT) mice.
Copyright This image is from Collette NM, Proc Natl Acad Sci U S A 2012 Aug 28;109(35):14092-7. Copyright 2012 National Academy of Sciences, U.S.A. J:188586
Associated
Alleles
Symbol Name
Rr20tm1.1Vlcg regulatory region 20; targeted mutation 1.1, Velocigene
Sosttm1(KOMP)Vlcg sclerostin; targeted mutation 1, Velocigene
Sosttm1(KOMP)Vlcg sclerostin; targeted mutation 1, Velocigene
Associated
Genotypes
Allelic Composition Genetic Background
Sosttm1(KOMP)Vlcg/Sosttm1(KOMP)Vlcg involves: C57BL/6NTac
Rr20tm1.1Vlcg/Rr20tm1.1Vlcg involves: 129S6/SvEvTac * C57BL/6NTac
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory