Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

Autophagosome accumulation in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ mice. A, Representative multimembrane structures (arrows) and autophagic vacuoles (arrowheads) in Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺ mouse heart at 4 months of age by transmission electron microscopy (TEM). Scale bar, 1 um.

This image is from Zhao T, J Biol Chem 2012 Jul 6;287(28):23615-25 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:188865

Associated
Alleles

Symbol	Name
Mfn2^tm1.1Mzhe	mitofusin 2; targeted mutation 1.1, Ming Zheng
Myl2^tm1(cre)Krc	myosin, light polypeptide 2, regulatory, cardiac, slow; targeted mutation 1, Kenneth R Chien

Associated
Genotypes

Allelic Composition	Genetic Background
Mfn2^tm1.1Mzhe/Mfn2^tm1.1Mzhe Myl2^tm1(cre)Krc/Myl2⁺	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6J

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24