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Phenotype Image Detail
Image
Caption (E) Comparison of the coat color phenotypes of three Atp7a mutants. Mice carrying the brown allele (Atp7aMo-3Btlr/Atp7a+, Atp7aMo-3Btlr/Y, or Atp7aMo-3Btlr/Atp7aMo-3Btlr), have brown fur and do not exhibit variegated pigmentation as is seen in Atp7aMo-2Btlr/Atp7a+ (Tigrou female), and Atp7aMo-Btlr/Atp7a+ (Tigrou-like female) females. Atp7aMo-2Btlr/Y (Tigrou male) mice lack pigmentation except at their extremities.
Copyright This image is from Siggs OM, Proc Natl Acad Sci U S A 2012 Aug 21;109(34):13733-8. Copyright 2012 National Academy of Sciences, U.S.A. J:188598
Associated
Alleles
Symbol Name
Atp7aMo-2Btlr ATPase, copper transporting, alpha polypeptide; mottled 2 Bruce Beutler
Atp7aMo-3Btlr ATPase, copper transporting, alpha polypeptide; mottled 3 Bruce Beutler
Atp7aMo-Btlr ATPase, copper transporting, alpha polypeptide; mottled Bruce Beutler
Associated
Genotypes
Allelic Composition Genetic Background
Atp7aMo-Btlr/Atp7a+ C57BL/6J-Atp7aMo-Btlr
Atp7aMo-2Btlr/Atp7a+ C57BL/6J-Atp7aMo-2Btlr
Atp7aMo-2Btlr/Y C57BL/6J-Atp7aMo-2Btlr
Atp7aMo-3Btlr/Atp7aMo-3Btlr C57BL/6J-Atp7aMo-3Btlr
Atp7aMo-3Btlr/Y C57BL/6J-Atp7aMo-3Btlr
Atp7aMo-3Btlr/Atp7a+ C57BL/6J-Atp7aMo-3Btlr

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory