Phenotype Image Detail

Image

Caption

(J) Eye circumference of Vsx2^or-J/Vsx2^tm1.1Eml (orJ/R227W) heterozygotes was intermediate to Vsx2^or-J/Vsx2^or-J (orJ) and Vsx2^tm1.1Eml/Vsx2^tm1.1Eml (R227W) homozygotes. (K-S) Expression of VSX2, CCND1, and TUBB3 in orJ, orJ/R227W, and R227W retinas at P0. VSX2 was detected in the orJ/R227W retina only. CCND1 and TUBB3 were detected in orJ or orJ/R227W retinas but not in R227W pigmented retina.

This image is from Zou C, PLoS Genet 2012 Sep;8(9):e1002924, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:190452

Associated
Alleles

Symbol	Name
Vsx2^or-J	visual system homeobox 2; ocular retardation Jackson
Vsx2^tm1.1Eml	visual system homeobox 2; targeted mutation 1.1, Edward M Levine

Associated
Genotypes

Allelic Composition	Genetic Background
Vsx2^tm1.1Eml/Vsx2^tm1.1Eml	involves: 129S1/Sv * 129X1/SvJ
Vsx2^or-J/Vsx2^or-J	involves: 129S1/Sv
Vsx2^or-J/Vsx2^tm1.1Eml	involves: 129S1/Sv * 129X1/SvJ

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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