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| Caption | Progressive retinal degeneration and increased susceptibility to light damage in Mirc35hgGt(D016D06)Wrst/Mirc35hgGt(D016D06)Wrst (miR-183CGT/GT) mice. (A-C) (Left) H&E staining of sagittal sections of the retina of 5-week- (A), 6-month- (B), and 1-year-old (C) mutant and wild-type (miR-183C+/+) littermate control mice. (Right) Measurements of the thickness the outer nuclear layer (ONL) (Upper) and the number of nuclear layers of the ONL at different locations in reference to the optic nerve (Lower). Sup, superior; Inf, inferior. (D) H&E staining (Left) and measurement (Right) of the retina of 6-month-old mutant and wild-type littermate control mice 2 weeks after a 2-hour exposure to bright light. #P < 0.06; *P < 0.05; **P < 0.01; ***P < 0.001. | ||||
| Copyright | This image is from Lumayag S, Proc Natl Acad Sci U S A 2013 Feb 5;110(6):E507-16. Copyright 2013 National Academy of Sciences, U.S.A. J:193822 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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