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| Caption | Development of glomerulonephritis in Pkn1tm1Kik/Pkn1tm1Kik (Pkn1-/-) mice. Haematoxylin-eosin staining (HE, top) and immunofluorescence staining with anti-IgC antibodies (alpha IgG, middle) and anti-C3 antibodies (alpha C3, bottom) of kidney sections from 6-month-old wild-type (WT) and mutant mice. Glomeruli from some mutant kidneys has increased mesangial cell numbers and thickened basement membranes (top). IgG and complement component C3 deposition is evident in mesangial regions of mutants (middle and bottom). | ||||
| Copyright | This image is from Yasui T, Proc Natl Acad Sci U S A 2012 Dec 18;109(51):21022-7. Copyright 2012 National Academy of Sciences, U.S.A. J:193187 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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