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| Caption | Evidence of Mucin misfolding in Muc2wnn/Muc2+ (Win/+) mice. Intestinal tissue from Muc2wnn/Muc2+ mice was fixed with glutaraldehyde, embedded in resin, and semi-thin sections stained with toluidine blue. Note the variable degree of vacuolisation of the goblet cells in the base of the crypts in the proximal large intestine (solid white arrows) and the lack of/minimal vacuolisation in surface goblet cells in the proximal large intestine (hollow arrows), distal large intestine and small intestinal villi. Tissue from wild-type mice is shown for comparison. Scale bars = 20 um. | ||||
| Copyright | This image is from Heazlewood CK, PLoS Med 2008 Mar 4;5(3):e54, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:194148 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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