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| Caption | Blastocysts that are Uso1Gt(YTA025)Byg/Uso1Gt(YTA025)Byg (YTA025) or Uso1Gt(AW0562)Wtsi/Uso1Gt(AW0562)Wtsi (AW0562) have a dispersed Golgi architecture. Confocal laser scanning double immunofluorescence images (magnification 400x) of cells within cultured E3.5 blastocysts that were recovered from heterozygous Uso1 gene trapped mating pairs. Antibodies recognizing epitopes in the USO1 carboxyl-terminal domain (red fluorescence) or the Golgi protein GM130 (green fluorescence) were used. DAPI staining was used to mark cell nuclei (blue fluorescence). In cells from blastocysts containing immuno-detectable USO1, GM130 localizes near the cell nuclei, overlapping with USO1 protein, GM130 does not localize near the nucleus but is more dispersed throughout the cytoplasm. | ||||||
| Copyright | This image is from Kim S, PLoS One 2012;7(11):e50530, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195576 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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