| Image |
|
||||
| Caption | A, representative image of a heterozygous Nmnat2Gt(EUCE0262a08)Hmgu/Nmnat2+ (+/gt) pup and a homozygous Nmnat2Gt(EUCE0262a08)Hmgu/Nmnat2Gt(EUCE0262a08)Hmgu (gt/gt) pup just after birth (P0). Homozygous pups died at birth, due to a failure to initiate respiration (their lungs remained uninflated), and showed a distinctive hunched posture. Hunched posture was already evident in E18.5 embryos which showed signs of paralysis. Heterozygous pups and embryos were indistinguishable from wild-types (+/+) in this respect. B, representative bladders dissected from fixed wild-type, heterozygous and homozygous E18.5 embryos. Homozygous E18.5 embryos and P0 pups have massively swollen bladders. In contrast, heterozygous E18.5 embryos and P0 pups have normal bladders. | ||||
| Copyright | This image is from Hicks AN, PLoS One 2012;7(10):e47869, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192196 | ||||
|
Associated Alleles |
|
||||
|
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 11/19/2024 MGI 6.24 |
|
|
|
||
Analysis Tools