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Phenotype Image Detail
Image
Caption Fusion of lumbar vertebrae in Gnai3tm1Lbi/Gnai3tm1Lbi mice. (A) B6129F2 wild-type (B6129-Gnai3+/+), 5-day-old, showing wild-type morphology of the second through fifth lumbar vertebrae. (B) Gnai3tm1Lbi/Gnai3tm1Lbi 4-day-old on a 129S/SvEv background (129-Gnai3-/-), with partial fusion of the third and fourth lumbar vertebrae. (C) Gnai3tm1Lbi/Gnai3tm1Lbi 5-day-old on a C57BL/6 and 129S/SvEv background (B6129-Gnai3-/-), with fusion of the second, third, fourth, and fifth lumbar vertebrae. The fusion of the third and fourth vertebrae is more extensive than that seen in any Gnai3tm1Lbi/Gnai3tm1Lbi mouse on the 129S/SvEv background. (Magnification: 10X.)
Copyright This image is from Plummer NW, Proc Natl Acad Sci U S A 2012 Dec 26;109(52):21366-71. Copyright 2012 National Academy of Sciences, U.S.A. J:193170
Associated
Alleles
Symbol Name
Gnai3tm1Lbi G protein subunit alpha i3; targeted mutation 1, Lutz Birnbaumer
Associated
Genotypes
Allelic Composition Genetic Background
Gnai3tm1Lbi/Gnai3tm1Lbi involves: 129S/SvEv * C57BL/6
Gnai3tm1Lbi/Gnai3tm1Lbi involves: 129S/SvEv

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory