Phenotype Image Detail

Image

Caption

Genotypes of littermates from crosses of heterozygotes are always apparent by their size. Note that Arrdc3^{Gt(CSE513)Byg}/Arrdc3^{Gt(CSE513)Byg} (-/-) mice are smaller than either Arrdc3^{Gt(CSE513)Byg}/Arrdc3⁺ (+/-) or wild-type (+/+) mice. Inset shows closeup of the coat of the homozygous mutant. The light colored speckling is due to dandruff (flakes of dead skin), which is associated with very thin skin in homozygous mutants only. Animals shown are from the F5 generation; the wild-type mouse shows increased contribution to coat color from the 129 strain relative to its littermates.

This image is from Shea FF, PLoS One 2012;7(12):e50557, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195551

Associated
Alleles

Symbol	Name
Arrdc3^{Gt(CSE513)Byg}	arrestin domain containing 3; gene trap CSE513, BayGenomics

Associated
Genotypes

Allelic Composition	Genetic Background
Arrdc3^{Gt(CSE513)Byg}/Arrdc3^{Gt(CSE513)Byg}	B6.129P2-Arrdc3^{Gt(CSE513)Byg}

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