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| Caption | Smg1Gt(AG0297)Wtsi/Smg1+ mice have decreased viability compared with wild-type (WT) littermates. (A) Kaplan-Meier survival plot shows the significantly decreased viability of heterozygous mutant mice compared with WT littermates. Statistical significance was determined using Prism 5 software (GraphPad Software). H&E staining of paraffin-embedded sections shows key pathological findings observed in heterozygous mice [lymphomas (B), chronic inflammation (C), papillary adenocarcinoma (D), and steatosis (E)] and WT tissues for comparison [lung (F), spleen (G), and liver (H)]. | ||||
| Copyright | This image is from Roberts TL, Proc Natl Acad Sci U S A 2013 Jan 22;110(4):E285-94. Copyright 2013 National Academy of Sciences, U.S.A. J:193626 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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