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Phenotype Image Detail
Image
Caption Cd28tm1Ltu/Cd28tm1Ltu Foxp3tm4(YFP/icre)Ayr/Foxp3+ (Cd28-deltaTreg) mice develop autoimmunity with skin inflammation. (A) Gross appearance and lymph nodes and spleens from representative wild-type littermate control (labeled 1 and 3) and mutant (labeled 2 and 4) mice.
Copyright This image is from Zhang R, J Clin Invest 2013 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:194503
Associated
Alleles
Symbol Name
Cd28tm1Ltu CD28 antigen; targeted mutation 1, Laurence A Turka
Foxp3tm4(YFP/icre)Ayr forkhead box P3; targeted mutation 4, Alexander Y Rudensky
Associated
Genotypes
Allelic Composition Genetic Background
Cd28tm1Ltu/Cd28tm1Ltu
Foxp3tm4(YFP/icre)Ayr/Foxp3+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory