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| Caption | Severe osteopenia in Tg(Col1a1-cre)1Bek/0 Pkd1tm2Ggg/Pkd1tm2Ggg (Col1a1(3.6)-Cre;Pkd1flox/flox) adult mice. (B) Bone structure of femurs. MicroCT analyais revealed that the lower bone mass in conditional homozygous mice resulted from reductions in both trabecular BV/TV and cortical CtTh that were proportional to the reduction in Pkd1 gene doese. Data represent the mean +/- S.D. from five to six individual mice. *Significant different from control (Pkd1tm2Ggg) and #significant difference from Tg(Col1a1-cre)1Bek/0 Pkd1tm2Ggg/Pkd1+ (Col1a1(3.6)-Cre;Pkd1flox/+) mice at P<0.05, respectively. | ||||||
| Copyright | This image is from Qiu N, PLoS One 2012;7(9):e46038, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:191967 | ||||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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