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Caption | Comparison of mitochondrial respiratory function in Polgtm1Jiha/Polg+ (+/m, heterozygous mutator mice), Polgtm1Jiha/Polgtm1Jiha, (m/m, homozygous mutator mice), and Del(MTmt-Tk-mt-Nd5)1Jiha (Delta, mito-miceDelta) mice. Wild-type (WT). (A) Histochemical analysis of mitochondrial respiratory enzyme activities in the heart and kidney. Tissue sections were stained for cytochrome c oxidase (COX) (brown) and succinate dehydrogenase (SDH) (blue). Cells that had lost COX activity were detected as a blue color. The proportions of DmtDNA in the heart and kidney tissues from mito-miceDelta were 82.6%, and 79.1%, respectively. A scale bar, 50 um. | ||||||||
Copyright | This image is from Mito T, PLoS One 2013;8(2):e55789, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199416 | ||||||||
Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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