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Phenotype Image Detail
Image
Caption Sarcomeric maturation in Rhebtm1.1Otsu/Rhebtm1.1Otsu Tg(Myh6-cre)2182Mds/0 (Rheb-/-) hearts. A, electron microscopic analysis. At postnatal day 3 or 5, the sarcomere structures in both wild-type and mutant mice were immature, indicated by a narrow sarcomere width. At postnatal day 8, the width of the sarcomere became greater in wild-type mice but it remained narrow in the mutant mice, indicating that sarcomere maturation is impaired. Scale bar, 2.5 um.
Copyright This image is from Tamai T, J Biol Chem 2013 Apr 5;288(14):10176-87 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:197831
Associated
Alleles
Symbol Name
Rhebtm1.1Otsu Ras homolog enriched in brain; targeted mutation 1.1, Kinya Otsu
Tg(Myh6-cre)2182Mds transgene insertion 2182, Michael D Schneider
Associated
Genotypes
Allelic Composition Genetic Background
Rhebtm1.1Otsu/Rhebtm1.1Otsu
Tg(Myh6-cre)2182Mds/0
involves: 129 * C57BL/6J * FVB/N

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory