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| Caption | 5C, H&E-stained liver sections from control (Alb Ei24f/+) and Ei24tm1Hzha/Ei24tm1Hzha Speer6-ps1Tg(Alb-cre)21Mgn/0 (Alb Ei24f/f) mutant mice show disorganized hepatic lobules and swollen hepatocytes. Insets show higher magnification views. Bar, 50 um. D, gross anatomy of livers from mutant mice at 10 months of age demonstrates the development of multiple tumor-like protrusions (arrows). E, H&E staining of liver sections from mutant mice at 10 months ofage (first panel). The arrow indicates a tumor-like protrusion. Bar, 100 um. Higher magnification images of livers from controls (second panel) and Ei24-deficient mice (third panel, protrusion region) at 10 months of age. Bar, 20 um. | ||||||
| Copyright | This image is from Zhao YG, J Biol Chem 2012 Dec 7;287(50):42053-63 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:193420 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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