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Phenotype Image Detail
Image
Caption (F) Male urogenital systems of Tg(TRAMP)8247Ng/0 (TRAMP-WT) and Epn1tm1.1Wami/Epn1tm1.1Wami Epn2tm1Ocr/Epn2tm1Ocr Tg(Cdh5-cre/ERT2)CIVE23Mlia/0 Tg(TRAMP)8247Ng/0 (TRAMP-EC-iDKO) mice show prostate tumors. Blue dotted line indicates tumor in prostates. Mice were sacrificed at 36 weeks.
Copyright This image is from Pasula S, J Clin Invest 2012 Dec 3;122(12):4424-38 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193966
Associated
Alleles
Symbol Name
Epn1tm1.1Wami epsin 1; targeted mutation 1.1, Wang Min
Epn2tm1Ocr epsin 2; targeted mutation 1, Ottavio Cremona
Tg(Cdh5-cre/ERT2)CIVE23Mlia transgene insertion CIVE23, M Luisa Iruela-Arispe
Tg(TRAMP)8247Ng transgene insertion 8247, Norman M Greenberg
Associated
Genotypes
Allelic Composition Genetic Background
Epn1tm1.1Wami/Epn1tm1.1Wami
Epn2tm1Ocr/Epn2tm1Ocr
Tg(Cdh5-cre/ERT2)CIVE23Mlia/0
Tg(TRAMP)8247Ng/0
involves: 129X1/SvJ * C57BL/6 * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory