Phenotype Image Detail

Image

Caption

Phenotypic analysis of Itm2a mutant embryos. F-H, X-Gal staining of Itm2a^tm1.1Buck/Y (Itm2a^XcdKO/Y) (F), Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3⁺ (Pax3^Cre/+ Itm2a^XcdKO/Y) (G) and Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3^tm1(cre)Joe (Itm2a^XcdKO/Y Pax3^Cre/Cre) (H) embryos at E9.5. I-J, X-Gal staining of Itm2a^tm1.2Buck/Y (Itm2a^XKO/Y) (I), Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3⁺ (Pax3^GFP/+ Itm2a^XKO/Y) (J) and Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3^tm4Buck (Pax3^GFP/GFPItm2a^XKO/Y) (K) embryos at E11.5.

This image is from Lagha M, PLoS One 2013;8(5):e63143, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200546

Associated
Alleles

Symbol	Name
Itm2a^tm1.1Buck	integral membrane protein 2A; targeted mutation 1.1, Margaret E Buckingham
Itm2a^tm1.2Buck	integral membrane protein 2A; targeted mutation 1.2, Margaret E Buckingham
Pax3^tm1(cre)Joe	paired box 3; targeted mutation 1, Jonathan A Epstein
Pax3^tm4Buck	paired box 3; targeted mutation 4, Margaret Buckingham

Associated
Genotypes

Allelic Composition	Genetic Background
Itm2a^tm1.1Buck/Y	involves: C57BL/6
Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3⁺	involves: C57BL/6
Itm2a^tm1.1Buck/Y Pax3^tm1(cre)Joe/Pax3^tm1(cre)Joe	involves: C57BL/6
Itm2a^tm1.2Buck/Y Pax3^tm4Buck/Pax3^tm4Buck	involves: C57BL/6

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24