Phenotype Image Detail

Image

Caption

Crx^Rip/Crx⁺ retinal photoreceptors lack outer segments and possess very short inner segments. Transmission EM images in the dorsal-ventral midline plane taken through the central retinas of 1-month-old (A) wild-type (Crx^+/+) and (B) heterozygous mutant mice. mito, mitochondria; nuc, nucleus; olm, outer limiting membrane. Original magnification, x1,200. Scale bar: 2 um. (C) Transmission EM images in the dorsal-ventral midline plane taken through the central retinas of 1-month-old wild-type and heterozygous mutant mice, showing the presence of ciliary microtubules in the mutant photoreceptors. CM, ciliary microtubule. Original magnification, x5,000. Scale bar: 1 um.

This image is from Roger JE, J Clin Invest 2014 Jan 2;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:203337

Associated
Alleles

Symbol	Name
Crx^Rip	cone-rod homeobox; retina with immature photoreceptors

Associated
Genotypes

Allelic Composition	Genetic Background
Crx^Rip/Crx⁺	C57BL/6J-Crx^Rip

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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