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| Caption | Impaired dermal repair due to reduced myofibroblast activity in wounds of Nbeal2tm1Lex/Nbeal2tm1Lex (-/-) mice and severely diminished mature and pro-TGF-beta in mutant platelets. (A-C) Representative sections of wounds at 7 days after injury. Wounds of mutant mice display (A) reduced development of granulation tissue but similar epithelial wound closure (H&E staining), (B) reduced amounts of collagenous granulation tissue (central darker area in picrosirius red stain), (C) and severely diminished myofibroblast numbers per wound. Scale bar: 500 um. | ||||||
| Copyright | This image is from Deppermann C, J Clin Invest 2013 Jul 1;(): and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:201413 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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