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Phenotype Image Detail
Image
Caption H&E stained coronal sections from newborn Hltftm1.2Geno/Hltftm1.2Geno mouse brains. (A-C) Panel A, widespread vacuolation in the anterior commissure (*) and preoptic/ventral paladium (boxed region). Panel B, higher magnification of the cholinergic-rich ventral paladium involved in regulation of motivation and behavior. Panel C, extensive bilateral vacuolation in the motor cortex.
Copyright This image is from Helmer RA, PLoS One 2013;8(6):e66799, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:203735
Associated
Alleles
Symbol Name
Hltftm1.2Geno helicase-like transcription factor; targeted mutation 1.2, Genoway
Associated
Genotypes
Allelic Composition Genetic Background
Hltftm1.2Geno/Hltftm1.2Geno B6.129S2-Hltftm1.2Geno
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory