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| Caption | Increased distal convoluted tubule (DCT) fractional volume in Wnk1tm2.1Juha/Wnk1+ Tg(Pgk1-cre)1Lni/0 (WNK1+/FHHt) mice. Representative images of Na+-Cl- cotransporter (NCC) immunostaining in (Upper Left) Wnk1tm2.1Juha/Wnk1+ (WNK1+/i1lox) and (Upper Right) WNK1+/FHHt kidney sections. (Lower) DCT fractional volume, quantified as the number of intersections between DCTs (identified as NCC-positive nephron segments) and a 50-um grid, is increased in WNK1+/FHHt mice. Individual data are plotted, and the bar corresponds to the median. *P < 0.05 (Mann-Whitney nonparametric ranking test). | ||||||
| Copyright | This image is from Vidal-Petiot E, Proc Natl Acad Sci U S A 2013 Aug 27;110(35):14366-71. Copyright 2013 National Academy of Sciences, U.S.A. J:200742 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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