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| Caption | Absence of vascular defects in the skin of adult Igs1tm11(CAG-Bgeo,-Edn2)Nat/Igs1+ Tg(KRT5-cre)5132Jlj/0 (Z/Edn2;K5-Cre) mice. (Row 1) X-gal staining shows keratinocyte expression of the mutant knockin allele and efficient Cre-mediated recombination in the presence of the K5-Cre transgene. In the mutant mice, hyperpigmentation in the skin confirms the production of bioactive Edn2. No alterations in vascular architecture are apparent based on PECAM1 staining. (Scale bar: 100 um.) | ||||||
| Copyright | This image is from Rattner A, Proc Natl Acad Sci U S A 2013 Oct 1;110(40):E3830-E3839. Copyright 2013 National Academy of Sciences, U.S.A. J:201133 | ||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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