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Phenotype Image Detail
Image
Caption Knee joints from 3.6-month-old Errfi1tm3.1Gvw/Errfi1+ Tg(CMV-cre)1Cgn/0 (Mig-6delta/+;CMVcre) and Errfi1tm3.1Gvw/Errfi1tm3.1Gvw Tg(CMV-cre)1Cgn/0 (Mig-6delta/delta;CMVCre) mice. Errfi1tm3.1Gvw/Errfi1tm3.1Gvw Tg(CMV-cre)1Cgn/0 mice developed osteoarthritis-like disorder, phenocopying Errfi1tm1Gvw/Errfi1tm1Gvw mice.
Copyright This image is from Staal B, Proc Natl Acad Sci U S A 2014 Feb 18;111(7):2590-5. Copyright 2014 National Academy of Sciences, U.S.A. J:206807
Associated
Alleles
Symbol Name
Errfi1tm3.1Gvw ERBB receptor feedback inhibitor 1; targeted mutation 3.1, George F Vande Woude
Tg(CMV-cre)1Cgn transgene insertion 1, University of Cologne
Associated
Genotypes
Allelic Composition Genetic Background
Errfi1tm3.1Gvw/Errfi1tm3.1Gvw
Tg(CMV-cre)1Cgn/0 		involves: 129 * 129S4/SvJaeSor * BALB/cJ
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory