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Phenotype Image Detail
Image
Caption Ninj1tm1Gto/Ninj1tm1Gto (KO) mice have reduced leukocyte recruitment into the spinal cord injury with experimental autoimmune encephalomyelitis (EAE). A, representative immunostaining images in the spinal cord tissues of wild-type (WT) or mutant mice were taken with anti-CD45 (pan leukocytes), anti-F4/80 (macrophage), and anti-CD3 (T lymphocyte) antibodies. Scale bar: 50 um. B, the number of infiltrated immune cells in the spinal cord was counted in three mice per group: **, p < 0.01. C, representative images of hematoxylin eosin (H&E) staining showing a lesion area and myelin oligodendrocyte glycoprotein (MOG) staining (red) showing demyelination in the spinal cord of the WT or mutant mice.
Copyright This image is from Ahn BJ, J Biol Chem 2014 Feb 7;289(6):3328-38 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:209516
Associated
Alleles
Symbol Name
Ninj1tm1Gto ninjurin 1; targeted mutation 1, Goo Taeg Oh
Associated
Genotypes
Allelic Composition Genetic Background
Ninj1tm1Gto/Ninj1tm1Gto B6.129P2-Ninj1tm1Gto

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory