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Phenotype Image Detail
Image
Caption Attenuation of phenylephrine-induced cardiac hypertrophy in Cavin4tm1.2Tue/Cavin4tm1.2Tue (MURC-/-) mice. (A) Representative H&E staining of wild-type (WT) and mutant heart paraffin-embedded sections (A, Upper, Left) and measurement of relative myocyte cross-sectional area (A, Upper, Right). WT and mutant mice were infused with phenylephrine for 7 days with osmotic minipumps. Higher magnification images are shown (Lower). (Scale bars: 1 mm in Upper; and 50 um in Lower.) A bar graph showing cross-sectional areas relative to vehicle-treated WT mice.
Copyright This image is from Ogata T, Proc Natl Acad Sci U S A 2014 Mar 11;111(10):3811-6. Copyright 2014 National Academy of Sciences, U.S.A. J:207401
Associated
Alleles
Symbol Name
Cavin4tm1.2Tue caveolae associated 4; targeted mutation 1.2, Tomomi Ueyama
Associated
Genotypes
Allelic Composition Genetic Background
Cavin4tm1.2Tue/Cavin4tm1.2Tue involves: 129S1/Sv * 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory