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Phenotype Image Detail
Image
Caption 12-0-tetradecanoyl-phorbor-13-acetate (TPA) induced skin proliferation assessed using Ki67. For each condition, micrographs show overall morphology on H&E-stained sections (Left) and proliferation as assessed by Ki67 immunohistochemistry (Right). (Top) Vehicle and TPA-treated skin of wild-type (Plce+/+); (Middle) vehicle and TPA-treated skin of Plcl1tm1.1Matk/Plcl1tm1.1Matk (Plce-/-); (Bottom) vehicle and TPA-treated skin of Plcl1tm2.1Matk/Plcl1tm2.1Matk (PlceRAm/RAm) mice. (Scale bar, 100 um.)
Copyright This image is from Martins M, Proc Natl Acad Sci U S A 2014 Mar 18;111(11):4239-44. Copyright 2014 National Academy of Sciences, U.S.A. J:207384
Associated
Alleles
Symbol Name
Plcl1tm1.1Matk phospholipase C-like 1; targeted mutation 1.1, Matilda Katan
Plcl1tm2.1Matk phospholipase C-like 1; targeted mutation 2.1, Matilda Katan
Associated
Genotypes
Allelic Composition Genetic Background
Plcl1tm1.1Matk/Plcl1tm1.1Matk FVB.Cg-Plcl1tm1.1Matk
Plcl1tm2.1Matk/Plcl1tm2.1Matk FVB.Cg-Plcl1tm2.1Matk
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory