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Phenotype Image Detail
Image
Caption External views of E18.5 Dhrs3tm1(NCOM)Mfgc/Dhrs3tm1(NCOM)Mfgc mouse embryos. Null mutants have a noticeably different appearance compared to wild-type littermates, with smaller eyes, unfused eyelids, and a very prominent and consistent cleft palate. Arrow indicates clefting of the secondary palate.
Copyright This image is from Adams MK, J Biol Chem 2014 May 23;289(21):14868-80 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:214109
Associated
Alleles
Symbol Name
Dhrs3tm1(NCOM)Mfgc dehydrogenase/reductase 3; targeted mutation 1, Mammalian Functional Genomics Centre
Dhrs3tm1(NCOM)Mfgc dehydrogenase/reductase 3; targeted mutation 1, Mammalian Functional Genomics Centre
Associated
Genotypes
Allelic Composition Genetic Background
Dhrs3tm1(NCOM)Mfgc/Dhrs3tm1(NCOM)Mfgc involves: C57BL/6 * C57BL/6N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory