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Phenotype Image Detail
Image
Caption Hindlimb fusion of Bmp4tm4Blh/Bmp4tm4Blh Isl1tm1(cre)Sev/Isl1+ (Bmp4 cKO) mice. (F-J) Hindlimb fusion shown by gross appearance and by skeletal preparations of mutant mice. The fibulae are aberrantly located medially (I) or are absent (J) in the mutants. Red arrowheads indicate the ossified fibula.
Copyright This image is from Suzuki K, PLoS One 2012;7(9):e43453, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:192045
Associated
Alleles
Symbol Name
Bmp4tm4Blh bone morphogenetic protein 4; targeted mutation 4, Brigid L Hogan
Isl1tm1(cre)Sev ISL1 transcription factor, LIM/homeodomain; targeted mutation 1, Sylvia Evans
Associated
Genotypes
Allelic Composition Genetic Background
Bmp4tm4Blh/Bmp4tm4Blh
Isl1tm1(cre)Sev/Isl1+
involves: 129 * 129S6/SvEvTac

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory