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Phenotype Image Detail
Image
Caption Representative magnetic resonance images (MRI) of AAV1-CBA-Cre and AAV1-CBA-GFP injected Tsc1tm1Djk/Tsc1tm1Djk Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+ mouse brains. AAV1-CBA-Cre injected mouse brains showed abnormalities associated with the ventricular regions. (A) Multiple apparent subependymal nodules (arrowheads) were seen in the ventricles in the brains of two AAV1-CBA-Cre injected mice. First two images are from the same mouse. (B) Ventricles also appeared to have thickening of the ependymal lining (arrowheads; two left panels). (C) None of these abnormalities were observed in the control vector (AAV1-CBA-GFP)-injected brains
Copyright This image is from Prabhakar S, PLoS One 2013;8(5):e64224, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:221022
Associated
Alleles
Symbol Name
Gt(ROSA)26Sortm1Sho gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Stuart Orkin
Tsc1tm1Djk TSC complex subunit 1; targeted mutation 1, David J Kwiatkowski
Associated
Genotypes
Allelic Composition Genetic Background
Tsc1tm1Djk/Tsc1tm1Djk
Gt(ROSA)26Sortm1Sho/Gt(ROSA)26Sor+
involves: 129S4/SvJae * 129S4/SvJaeSor

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory