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Caption | Crxtm1.1Smgc/Crxtm1.1Smgc (E168d2/d2) and Crxtm2.1Smgc/Crxtm2.1Smgc (R90W/W) mice develop Leber Congenital Amaurosis (LCA)-like retinopathy as seen in Crxtm1Clc/Crxtm1Clc (-/-) mice. A-L. H&E staining of paraffin embedded sagittal retinal sections for Crxtm1.1Smgc/Crxtm1.1Smgc, Crxtm2.1Smgc/Crxtm2.1Smgc, and Crxtm1Clc/Crxtm1Clc (-/-) mutant mice at P14, 1 month and 3 months and imaged by light microscopy, showing the lack of photoreceptor outer segments (OS) and loss of outer nuclear layer (ONL) cells with age. | ||||||||
Copyright | This image is from Tran NM, PLoS Genet 2014 Feb;10(2):e1004111, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:211011 | ||||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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