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| Caption | Neutralization of BMP10 causes defective vascular development in Gdf2tm1Lex/Gdf2+ (Bmp9+/-) and Gdf2tm1Lex/Gdf2tm1Lex (Bmp9-/-) mice. (A) Fluorescence images of low (Top) and higher magnification (Middle and Bottom) of retinal vasculature. Neonatal mice were treated with PBS or anti-BMP10 (462732; R&D Systems) on P2 and P4, at 10 mg/kg. Whole mount P7 mouse retinas were stained with isolectin B4 to visualize overall vasculature, and anti-alphaSMA for arteries. Dotted line at Middle marks the edge of retinal cup. (Scale bars: Top, 500 um; Middle, 200 um; Bottom, 25 um.) | ||||||
| Copyright | This image is from Chen H, Proc Natl Acad Sci U S A 2013 Jul 16;110(29):11887-92. Copyright 2013 National Academy of Sciences, U.S.A. J:222016 | ||||||
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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