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| Caption | Histology of colon tissue from Muc2tm1Avel/Muc2tm1Avel (Muc2-/-) mice. (A) Carnoy fixed whole colon sections with preserved mucus from wild-type (WT) and mutant mice were analyzed by FISH (red) for bacteria localization and counterstained with DAPI. The mucus separating bacteria from the epithelium in WT mice is indicated by a double arrow and bacteria in contact with the epithelium in mutant mice are marked by arrows. Scale bars are 100 um. (C-D) Representative sections from the proximal, middle or distal colon from (C) heterozygous control (18 weeks of age) and (D) inflamed homozygous mutant (18 weeks of age) are shown. The neutrophil frequency determined by flow cytometry in parallel samples of the displayed tissues is indicated in the inlays. Original magnification is 5x. | ||||
| Copyright | This image is from Wenzel UA, PLoS One 2014;9(6):e100217, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:216831 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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