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| Caption | RNA oxidation in Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 mouse brain. (A-D) Survey of 8-OH(d)G immunoreactivity in brain tissue from Glultm1.1Geno/Glultm1.1Geno (Glulfl/fl) (Left) and Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 (Glulfl/fl x Alb-Cre+) (Right) mice is presented in the absence (Lower) or presence (Upper) of costaining with GFAP (green) and Hoechst 34580 (blue). One representative of the cerebellum (A), hippocampus (B), somatosensory cortex (C), and piriform cortex (D) of n = 5 is demonstrated. (Scale bars: A, 100 um; B-D, 200 um.) (E) Samples harvested from brain sections (from left to right: cerebellum, hippocampus, somatosensory cortex, and piriform cortex) of Glultm1.1Geno/Glultm1.1Geno and Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 mice were tested for RNA oxidation expression using Northwestern blotting [n = 6 for homozygous mice, n = 9 (cerebellum, hippocampus,and piriform cortex) and n = 10 (somatosensory cortex) for Glultm1.1Geno/Glultm1.1Geno Speer6-ps1Tg(Alb-cre)21Mgn/0 mice. | ||||||
| Copyright | This image is from Qvartskhava N, Proc Natl Acad Sci U S A 2015 Apr 28;112(17):5521-6. Copyright 2015 National Academy of Sciences, U.S.A. J:221031 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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