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Phenotype Image Detail
Image
Caption Images of sections immunostained with CD31 to visualize blood vessel lumens in the brain of E13.5 wild-type (Dock4 WT) and Dock4tm1(NCOM)Mfgc/Dock4+ (Dock4 Het) embryos. Scale bar, 50 um. i-iv: magnifications of areas outlined in larger images. Red arrows point to blood cells in small calibre lumens. Table shows analysis of lumen size (three embryos for each condition) in microscopic fields across the whole hemisphere. 40 vessels with largest diameter lumens were analysed for each embryo.
Copyright This image is from Abraham S, Nat Commun 2015;6():7286, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:224385
Associated
Alleles
Symbol Name
Dock4tm1(NCOM)Mfgc dedicator of cytokinesis 4; targeted mutation 1, Mammalian Functional Genomics Centre
Dock4tm1(NCOM)Mfgc dedicator of cytokinesis 4; targeted mutation 1, Mammalian Functional Genomics Centre
Associated
Genotypes
Allelic Composition Genetic Background
Dock4tm1(NCOM)Mfgc/Dock4+ involves: C57BL/6J * C57BL/6NCrl

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory