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Phenotype Image Detail
Image
Caption Fen1tm3.1Bhsh/Fen1tm3.1Bhsh mice accumulate apoptotic DNA in tissues as a result of retarded apoptotic DNA degradation and increased DNA damage induced apoptosis. (a) Accumulation of apoptotic nuclei in the mutant tissues. Kidney and lung tissue sections were concurrently stained with DAPI (blue) and TUNEL (red). Pink spots in merged views were scored as TUNEL-positive nuclei. Scale bar, 100 um.
Copyright This image is from Zheng L, Nat Med 2007 Jul;13(7):812-9 and is displayed with the permission of The Nature Publishing Group who owns the Copyright. J:231218
Associated
Alleles
Symbol Name
Fen1tm3.1Bhsh flap structure specific endonuclease 1; targeted mutation 3.1, Binghui Shen
Associated
Genotypes
Allelic Composition Genetic Background
Fen1tm3.1Bhsh/Fen1tm3.1Bhsh Not Specified

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory