Phenotype Image Detail

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Phenotype Image Detail

Image

Caption

A thin cornea (black arrows in A) and iridocorneal dysgenesis (black arrowheads in B) were observed in the Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/0 Tgfb2^tm1Doe/Tgfb2⁺ mutants at E18.5.

This image is from Iwao K, J Clin Invest 2009 Jul;119(7):1997-2008 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152572

Associated
Alleles

Symbol	Name
Ext1^tm1Yama	exostosin glycosyltransferase 1; targeted mutation 1, Yu Yamaguchi
H2az2^{Tg(Wnt1-cre)11Rth}	H2A.Z histone variant 2; transgene insertion 11, David H Rowitch
Tgfb2^tm1Doe	transforming growth factor, beta 2; targeted mutation 1, Thomas Doetschman

Associated
Genotypes

Allelic Composition	Genetic Background
Ext1^tm1Yama/Ext1⁺ H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ Tgfb2^tm1Doe/Tgfb2⁺	B6.Cg-Tgfb2^tm1Doe H2az2^{Tg(Wnt1-cre)11Rth} Ext1^tm1Yama

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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