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| Caption | Growth retardation, facial dysmorphism, and spine curvature. A, 1-month-old Gnptabnym/Gnptabnym (nym/nym) mice show reduced body size and skeletal abnormalities (e.g. facial dysmorphism and curvature of the spine) in comparison with wild-type (+/+) littermates. C, Facial phenotype progresses with age. Particularly evident is the thickening of the eyelids. D, Whole body exotic dorso-ventral view of the 12-month-old mutant mouse (left) and whole body exotic lateral view of the 12-month-old mutant mouse (right). White arrows, abnormal curvature (left) and hunched back (right). Values are expressed as mean +/- S.E. (error bars) (n = 8; *, p < 0.05; **, p <0.01; ***, p <0.001; ****, p < 0.0001). | ||||
| Copyright | This image is from Paton L, J Biol Chem 2014 Sep 26;289(39):26709-21 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:218156 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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