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| Caption | Commd9Gt(AQ0362)Wtsi/Commd9Gt(AQ0362)Wtsi (KO) embryos display neural tube edema (white arrows), seen by E10.5 (left). This is followed by punctate hemorrhages (yellow arrows), seen at E11.5 (right). WT, wild-type. Bar, 500 um. (C) Mutant embryos eventually developed widespread hemorrhages that are apparent by E11.5 and at later stages. Bar, 500 um. (D) Cross-sectional histologic analysis demonstrated small hypoplastic hearts in all the mutant embryos. Bar, 200 um. (E) Areas of unilateral narrowing of the dorsal aorta were commonly seen in mutant embryos (arrow). Bar, 100 um. | ||||
| Copyright | This image is from Li H, J Cell Biol 2015 Nov 9;211(3):605-17, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:230747 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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