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| Caption | Skeletal abnormalities in Rps7Zma/Rps7+ mutants.(A, B) Comparative X-rays of adult wild-type (WT) (A) and mutant (B) mice show severe vertebral fusion leading to tail kinking in the mutant. (C-H) Alcian blue and alizarin red skeletal staining of late gestation WT (C, E, G) and heterozygous mutant (D, F, H) embryos. (C, D) Disorganization within the neural arches of the mutant is evident in a dorsal view of the cervical vertebrae. (E, F) Asymmetric attachment of 8 ribs to the sternum (arrow) and a shortened first sternebrae (*) are indicated in the mutant. (G, H) Delayed development and disorganization of the ossification centers is apparent in the lumbar and sacral vertebrae. The sacral vertebrae show abnormal fusing of additional vertebrae (bracketed region). Scale bars: C,D,G,H = 2 mm; E,F = 200 um. | ||||
| Copyright | This image is from Watkins-Chow DE, PLoS Genet 2013 Jan;9(1):e1003094, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:195156 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 06/12/2024 MGI 6.13 |
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