About   Help   FAQ
Phenotype Image Detail
Image
Caption H&E staining of decidua containing embryos did not reveal morphological abnormalities between wild-type (wt) and heterozygous Gpx4tm4Marc mutant (wt/ser) embryos. In Gpx4tm4Marc/Gpx4tm4Marc (ser/ser) embryos, however, intrauterine resorptions of embryonic tissue were evident. Moreover, a clear distinction of the embryonic part in the three germinal layers was not unequivocally possible in contrast to heterozygous and wild-type embryos. Am, amnion; CH, chorion; EC, ectoderm; EM, embryonic tissue; EN, endoderm; EX, extraembryonic tissue; ME, mesoderm. Scale bars: white, 100 um; black, 50 um).
Copyright This image is from Ingold I, J Biol Chem 2015 Jun 5;290(23):14668-78 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:225651
Associated
Alleles
Symbol Name
Gpx4tm4Marc glutathione peroxidase 4; targeted mutation 4, Marcus Conrad
Associated
Genotypes
Allelic Composition Genetic Background
Gpx4tm4Marc/Gpx4tm4Marc involves: 129S6/SvEvTac * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory