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| Caption | Synj2mozart/Synj2mozart (Synj2N538K/N538K) cochleae exhibit degeneration. Wild-type (Synj2+/+) (Panels A, B and C) and mutant (Panels D, E and F) cochleae were sectioned at 4 (Panels A and D), 8 (Panels B and E) and 12 (Panels C and F) weeks of age and H&E stained. Representative cochleae are shown. Mutant cochleae show signs of degeneration at 8 and 12 weeks of age, with evidence of collapse of the organ of Corti (arrow head, panels E and F) and degeneration of spiral ganglion neurons (arrow, panels E and F). SG, spiral ganglion; OC, organ of corti; OHC, outer hair cells; IHC, inner hair cell. Scale bar: 100 um. | ||||
| Copyright | This image is from Manji SS, PLoS One 2011;6(3):e17607, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171701 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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