Phenotype Image Detail

About Help FAQ

Phenotype Image Detail

Image

Caption

(C) Representative cecal pathology of E. histolytica-challenged but uninfected at day 3 animals showed nearly normal-looking morphology or a mild submucosal edema (top left and right). While infected wild-type (QQ) mice mainly exhibited submucosal edema and epithelial hyperplasia (bottom left), the infected Lepr^tm1.1Rll/Lepr^tm1.1Rll (R/R) cecum displayed marked mucosal destruction/ulceration and inflammation. E. histolytica trophozoites are indicated by arrows (bottom right and insert). Original magnification, x40; x 200 (inset).

This image is from Duggal P, J Clin Invest 2011 Mar 1;121(3):1191-8 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:172012

Associated
Alleles

Symbol	Name
Lepr^tm1.1Rll	leptin receptor; targeted mutation 1.1, Rudolph L Leibel

Associated
Genotypes

Allelic Composition	Genetic Background
Lepr^tm1.1Rll/Lepr^tm1.1Rll	129P3/J-Lepr^tm1.1Rll

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/29/2024 MGI 6.24