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Phenotype Image Detail
Image
Caption Fluorescent images of E9.5-10.5 DAPI stained (a) wild-type and (b) Aldh1a2grim/Aldh1a2grim (grimace) embryos. Abbreviations: ba, branchial arch; lnp, lateral nasal process; md, mandibular process; mnp, medial nasal process, ma, maxillary process; np, nasal placode; op, optic vesicle; ov, otic vesicle. Arrowheads highlight agenesis, hyopoplasia and abnormal patterning and development of the pharyngeal arches in mutant embryos compared to wild-type.
Copyright This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522
Associated
Alleles
Symbol Name
Aldh1a2grim aldehyde dehydrogenase family 1, subfamily A2; grimace
Associated
Genotypes
Allelic Composition Genetic Background
Aldh1a2grim/Aldh1a2grim involves: 129S1/Sv * C57BL/6 * FVB/NJ

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory