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| Caption | Ccr6tm1.1Jmf/Ccr6tm1.1Jmf mice are resistant to IL23-induced acanthosis and dermal inflammation. Ears of wild-type (WT) and mutant mice were injected intradermally every other day for 16 days with 20ul PBS, either alone or containing 500 ng IL-23. (B) H&E-stained sections of PBS- or IL-23-injected ears from WT and mutant mice at day 15. k, hyperparakeratosis with intracorneal neutrophilic pustule; a, acanthosis; b, increased proliferative activity of basal layer epidermal keratinocytes; d, dermal mononuclear cell infiltrate; v, telangiectasia of dermal blood vessels. Sections are representative of 2 experiments. | ||||
| Copyright | This image is from Hedrick MN, J Clin Invest 2009 Aug;119(8):2317-29 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152716 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/19/2024 MGI 6.24 |
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