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Phenotype Image Detail
Image
Caption Coronal sections of Pkd1tm2.2Bol/Pkd1tm3.1Bol Tg(Nes-cre)1Kln/0 (Pkd1Flox/deltaC;Nestin-Cre) brains (D, F, H) and the control brains (C, E, G) at P8 stained with hematoxylin-eosin show hydrocephalus with dilatation of the third ventricle (arrow). (I, J) Coronal sections of mutant (J) and control (I) brains at P10 show dilatation of the lateral ventricles (arrow). Scale bar C-J 1 mm.
Copyright This image is from Wodarczyk C, PLoS One 2009;4(9):e7137, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:153606
Associated
Alleles
Symbol Name
Pkd1tm2.2Bol polycystin 1, transient receptor potential channel interacting; targeted mutation 2.2, Alessandra Boletta
Pkd1tm3.1Bol polycystin 1, transient receptor potential channel interacting; targeted mutation 3.1, Alessandra Boletta
Tg(Nes-cre)1Kln transgene insertion 1, Rudiger Klein
Associated
Genotypes
Allelic Composition Genetic Background
Pkd1tm2.2Bol/Pkd1tm3.1Bol
Tg(Nes-cre)1Kln/0
involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac * SJL

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory