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| Caption | VEGF-C-and galectin-8-induced lymphangiogenesis is diminished in Pdpntm2.1Mlkn/Pdpntm2.1Mlkn Tg(CAG-cre/Esr1*)5Amc/0 (PDPN KO) mice. VEGF-C pellets (160 ng) (N = 10) (g) and galectin-8 pellets (160 ng) (N = 9) (h) were implanted into wild-type (WT) and mutant mice. After 7 days post implantation, the corneal flat mounts were stained anti-LYVE-1 and lymphatic vessel areas were quantified. Representative fluorescence images from each group are shown. Asterisks indicate pellets. Data are plotted as mean s.e.m. and analysed using Student's t-test. *P < 0.05, **P < 0.01, ***P < 0.001 versus corresponding control or WT mice. Scale bars: 200 um (g,h). | ||||||
| Copyright | This image is from Chen WS, Nat Commun 2016;7():11302, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:235778 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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